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TWiST Strengthens PARP Inhibitor Role in Ovarian Cancer
Monday, March 18, 2019
New analysis of the NOVA trial confirms clinical benefit from niraparib for patients with recurrent ovarian cancer. The benefit occurred both in patients with and in those without BRCA mutations. Medscape Medical News
Ripple Effect: Repackaged Losartan Recalled Due to Impurity
Monday, March 18, 2019
Legacy Pharmaceutical recalls 43 repackaged lots of losartan because of the presence of the probable carcinogen N-nitroso-N-methyl-4-aminobutyric acid (NMBA) in the active pharmaceutical ingredient. News Alerts
Immunotherapy Should Be First Line in Merkel Cell Carcinoma
Monday, March 18, 2019
Pembrolizumab demonstrated durable tumor control, a generally manageable safety profile, and favorable survival outcomes compared with historical data in advanced MCC. Medscape Medical News
From Bench to Bedside: ENDO 2019 Ties Science to Clinical Care
Monday, March 18, 2019
'What distinguishes ENDO from other meetings is that you get a curated view of what is the newest, hottest, and best in science, which you know...is going to be impacting care.' Medscape Medical News
Chemo for Early-Stage Prostate Cancer? RTOG 0521 Says Maybe
Monday, March 18, 2019
In major clinical trial, docetaxel, which is typically used in metastatic disease, improved outcomes in high-risk, early-stage disease. However, the survival results fell short of the trial target. Medscape Medical News
Phone Intervention for Patients Most At Risk Improves HbA1c
Monday, March 18, 2019
Pharmacist-led phone interventions to improve insulin adherence in patients with diabetes worked best when those at highest risk of noncompliance were targeted. Medscape Medical News
Stroke Mortality Down, but Global Burden Remains High
Monday, March 18, 2019
Although the global stroke mortality rate dropped substantially from 1990 to 2016, the global burden of stroke is still high, with more than 80 million stroke survivors, new data show. Medscape Medical News
WRAP-IT: Antibacterial Pouch Cuts Device Infections
Monday, March 18, 2019
The trial provides the first randomized data supporting prophylaxis with the long-available TYRX envelope, but cost continues to be a consideration. Medscape Medical News
Lifestyle Changes Do a Number on PSA Values
Monday, March 18, 2019
Two month's abstinence from a few of life's pleasures obviated the need for prostate biopsy in nearly half of men who adopted the lifestyle changes. Medscape Medical News
Novel Program Trains Nurse Practitioners to Manage Pain Patients
Monday, March 18, 2019
In a unique educational program, nurse practitioners learned how to examine patients with shoulder and knee pain and how to determine which patients require specialist referral. Medscape Medical News
Hopeful Heart: Team Care for Mood Plus HF Improves Wellbeing
Monday, March 18, 2019
There is hope for improving mood and quality of life for heart failure patients with depression, a new trial suggests. Two-pronged care by a nurse care manager plus a diverse team topped usual care. Medscape Medical News
Could Ultrasound Serve as an Early Bone Density Screening Tool?
Monday, March 18, 2019
A small study suggests ultrasound of the heel bone could be a preliminary way of assessing bone density. The idea has been around for more than 30 years but has never taken off, says an expert. Medscape Medical News
Autism, Depression Tied to Prenatal Maternal Infection
Monday, March 18, 2019
A study of more than 1.5 million children suggests those who had been exposed to maternal infection in utero are at significantly greater risk of developing autism or depression during their lifetime. Medscape Medical News
TAVR Low-Risk Studies Get Standing Ovation at ACC
Monday, March 18, 2019
The success of the two trials of transcatheter aortic valve replacement in low-surgical-risk patients stole the show at the ACC today. Medscape Medical News
New AHA/ACC CVD Primary Prevention Guideline
Sunday, March 17, 2019
As expected, the new document recommends generally against aspirin in primary prevention, and aims to make a 'one-stop shop' for clinicians. Medscape Medical News
AUGUSTUS Backs Apixaban 'Double Therapy' in Most AF Post-ACS, PCI
Sunday, March 17, 2019
The most safe and effective antithrombotic regimen may involve neither warfarin nor aspirin, suggested a trial that might allay bleeding-risk concerns in a tough-to-treat atrial fibrillation population. Medscape Medical News
Apple Watch Helps Detect AF: Is This the Future?
Saturday, March 16, 2019
The first study of its kind involving more than 400,000 members of the general population used an Apple Watch to identify irregular pulse and received a mixed response from ACC delegates. Medscape Medical News
HoT-PE Puts Early Discharge for Low-Risk PE on Front Burner
Saturday, March 16, 2019
The findings strengthen consideration of home treatment for patients at sufficiently low risk and raise the issue of whether hospital admission is a necessary step at all. Medscape Medical News
CABANA Published: Mixed Results, Helpful Insights
Saturday, March 16, 2019
Primary clinical outcomes were similar for catheter ablation and meds-only in the atrial fibrillation trial. But secondary ablation advantages could help inform shared decision-making, say observers. Medscape Medical News
TAVR With Evolut: Interim Results Promising in Low-Risk Patients
Saturday, March 16, 2019
The transcatheter procedure was noninferior to surgery in an interim Bayesian analysis of the primary endpoint -- death from any cause or disabling stroke at 24 months -- in a new trial involving patients with severe aortic stenosis at low surgica...